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E34.321

ICD-10-CM 2027 · Billable

Primary insulin-like growth factor-1 (IGF-1) deficiency

Sibling codes

  • E34.322 – Insulin-like growth factor-1 (IGF-1) resistance
  • E34.328 – Other genetic causes of short stature
  • E34.329 – Unspecified genetic causes of short stature

Inclusion terms

  • Acid-labile subunit gene (IGFALS) defect
  • Growth hormone gene 1 (GH1) defect with growth hormone neutralizing antibodies
  • Growth hormone insensitivity syndrome (GHIS)
  • Insulin-like growth factor 1 gene (IGF1) defect
  • Laron type short stature
  • Severe primary insulin-like growth factor-1 deficiency (SPIGFD)
  • Signal transducer and activator of transcription 5B gene (STAT5b) defect

Inherited from E34.3: Short stature due to endocrine disorder

Excludes1

  • achondroplastic short stature (Q77.4)
  • hypochondroplastic short stature (Q77.4)
  • nutritional short stature (E45)
  • pituitary short stature (E23.0)
  • progeria (E34.8)
  • renal short stature (N25.0)
  • Russell-Silver syndrome (Q87.19)
  • short-limbed stature with immunodeficiency (D82.2)
  • short stature (child) (R62.52)
  • short stature in specific dysmorphic syndromes - code to syndrome - see Alphabetical Index
  • short stature NOS (R62.52)

Inherited from E34: Other endocrine disorders

Excludes1

  • pseudohypoparathyroidism (E20.1)

Part of: E34.32: Genetic causes of short stature › E34.3: Short stature due to endocrine disorder › E34: Other endocrine disorders