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R65.21

ICD-10-CM 2027 · Billable

Severe sepsis with septic shock

Sibling codes

  • R65.20 – Severe sepsis without septic shock

Excludes1

  • postprocedural septic shock (T81.12-)

Inherited from R65.2: Severe sepsis

Code first

  • underlying infection, such as: infection following a procedure (T81.4-)
  • infections following infusion, transfusion and therapeutic injection (T80.2-)
  • puerperal sepsis (O85)
  • sepsis following complete or unspecified spontaneous abortion (O03.87)
  • sepsis following ectopic and molar pregnancy (O08.82)
  • sepsis following incomplete spontaneous abortion (O03.37)
  • sepsis following (induced) termination of pregnancy (O04.87)
  • sepsis NOS (A41.9)

Inclusion terms

  • Infection with associated acute organ dysfunction
  • Sepsis with acute organ dysfunction
  • Sepsis with multiple organ dysfunction
  • Systemic inflammatory response syndrome due to infectious process with acute organ dysfunction

Use additional code

  • code to identify specific acute organ dysfunction, such as:
  • acute kidney failure (N17.-)
  • acute respiratory failure (J96.0-)
  • critical illness myopathy (G72.81)
  • critical illness polyneuropathy (G62.81)
  • disseminated intravascular coagulopathy [DIC] (D65)
  • encephalopathy (metabolic) (septic) (G93.41)
  • hepatic failure (K72.0-)

Part of: R65.2: Severe sepsis › R65: Symptoms and signs specifically associated with systemic inflammation and infection