1A04

ICD-11 MMS 2026-01

Intestinal infections due to Clostridioides difficile

Description

A disease of the colon, caused by an infection with toxigenic strains of the gram-positive bacteria Clostridioides difficile (formerly known as Clostridium difficile). This disease is characterised by colitis, diarrhoea, abdominal pain, and fever. Transmission is commonly by direct or indirect contact. A disturbance of the normal bacterial flora of the colon, e.g. due to antibiotic treatment, facilitates the development of an intestinal infection with Clostridioides difficile. Confirmation is by identification of Clostridioides difficile in a faecal sample.

Index terms

  • Intestinal infections due to Clostridioides difficile
  • C diff colitis
  • C difficile
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  • C difficile infection
  • C. difficile colitis
  • CDAD – [clostridioides difficile associated diarrhoea]
  • CDAD – [clostridium difficile associated diarrhoea]
  • Clostridium difficile colitis
  • Clostridium difficile diarrhoea
  • Clostridium difficile gastroenteritis
  • colitis due to Clostridium difficile
  • enterocolitis due to Clostridium difficile
  • foodborne clostridium difficile infection
  • necrotizing enterocolitis due to clostridium difficile infection
  • Pseudomembranous colitis
  • PMC - [pseudomembranous colitis]
  • Megacolon due to Clostridioides difficile
  • megacolon due to Clostridium difficile

Inclusions

  • Pseudomembranous colitis

Excludes

  • KB88 – Necrotising enterocolitis of newborn

Exclusions from above levels

  • DA42.1 – Helicobacter pylori induced gastritis
  • DA51.0 – Helicobacter-pylori associated duodenitis
  • DA60.1 – Helicobacter pylori associated gastric ulcer
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  • DA60.2 – Helicobacter pylori associated and drug-induced gastric ulcer
  • DA63.1 – Helicobacter-pylori associated duodenal ulcer
  • DA63.2 – Helicobacter-pylori associated and drug-induced duodenal ulcer
  • http://id.who.int/icd/entity/1834648119 – Bacterial foodborne intoxications
  • NE83.1 – Infection arising from device, implant or graft, not elsewhere classified

Sibling codes

  • 1A00 – Cholera
  • 1A01 – Intestinal infection due to other Vibrio
  • 1A02 – Intestinal infections due to Shigella
  • 1A03 – Intestinal infections due to Escherichia coli
  • 1A05 – Intestinal infections due to Yersinia enterocolitica
  • 1A06 – Gastroenteritis due to Campylobacter
  • 1A07 – Typhoid fever
  • 1A08 – Paratyphoid fever
  • 1A09 – Infections due to other Salmonella
  • 1A0Y – Other specified bacterial intestinal infections
  • 1A0Z – Bacterial intestinal infections, unspecified

Foundation entity

Intestinal infections due to Clostridioides difficile – http://id.who.int/icd/entity/250688797

Allowed postcoordination axes

Part of: 01: Certain infectious or parasitic diseases