1F00.21

ICD-11 MMS 2026-01

Encephalitis due to herpes simplex virus

Description

Herpetic encephalitis is a cerebral infection caused by herpes simplex virus type 1 (HSV1). It presents as acute necrosing temporal encephalitis. Onset is rapid (less than 48 hours) with a fever of 40 °C, headaches, and behavioural, language and memory problems. These initial manifestations are followed by numbness and coma, which may be accompanied by convulsions and paralysis. This disease, which affects only a small minority of HSV1-infected individuals, results from a primary immune deficiency.

Index terms

  • Encephalitis due to herpes simplex virus
  • HSV - [herpes simplex virus] encephalitis
  • encephalitis due to herpesviridae
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  • encephalitis due to herpesvirus
  • herpes encephalitis
  • herpes simplex encephalitis
  • herpes simplex encephalomyelitis
  • herpes simplex neuroinvasion
  • herpes virus encephalitis
  • herpesviral encephalitis
  • herpetic encephalitis
  • herpetic encephalopathy
  • Encephalitis due to herpes simplex type 1
  • Encephalitis due to herpes simplex type 2
  • Herpesviral meningoencephalitis
  • Encephalitis due to Human herpesvirus

Exclusions from above levels

  • 1F05.1 – Herpangina
  • NE83.1 – Infection arising from device, implant or graft, not elsewhere classified

Sibling codes

  • 1F00.20 – Herpes simplex meningitis
  • 1F00.2Y – Other specified herpes simplex infection of central nervous system
  • 1F00.2Z – Herpes simplex infection of central nervous system, unspecified

Foundation entity

Encephalitis due to herpes simplex virus – http://id.who.int/icd/entity/320069644

Part of: 1F00.2: Herpes simplex infection of central nervous system › 1F00: Herpes simplex infections › 01: Certain infectious or parasitic diseases