2B68

ICD-11 MMS 2026-01

Malignant neoplasms of submandibular or sublingual glands

Description

Salivary gland tumours can show a striking range of morphological diversity between different tumour types and sometimes within an individual tumour mass. In addition, hybrid tumours, dedifferentiation and the propensity for some benign tumours to progress to malignancy can confound histopathological interpretation. These features, together with the relative rarity of a number of tumours, can sometimes make diagnosis difficult, despite the abundance of named tumour entities. The increasing use of pre-operative fine needle aspiration biopsies also needs to be taken into account, as artifactual changes may be superimposed on the tumours. Unfortunately, the morphological variability of these tumours is mirrored by the immunocytochemical profiles, so that special stains are rarely useful in routine diagnosis of salivary gland epithelial neoplasms.

Coding note from above levels

For use of this category, reference should be made to the mortality coding rules and guidelines in the Reference Guide.

Excludes

  • 2B67 – Malignant neoplasms of parotid gland
  • http://id.who.int/icd/entity/1965082709 – Malignant mesenchymal neoplasms

Exclusions from above levels

  • http://id.who.int/icd/entity/879154182 – Neoplasms of central nervous system or related structures
  • http://id.who.int/icd/entity/944754984 – Neoplasms of haematopoietic or lymphoid tissues

Child codes

  • 2B68.0 – Adenocarcinoma of submandibular or sublingual glands
  • 2B68.1 – Squamous cell carcinoma of submandibular or sublingual glands
  • 2B68.2 – Other specified malignant neoplasms of submandibular or sublingual glands
  • 2B68.Z – Malignant neoplasms of submandibular or sublingual glands, unspecified

Sibling codes

  • 2B60 – Malignant neoplasms of lip
  • 2B61 – Malignant neoplasms of base of tongue
  • 2B62 – Malignant neoplasms of other or unspecified parts of tongue
  • 2B63 – Malignant neoplasms of gum
  • 2B64 – Malignant neoplasms of floor of mouth
  • 2B65 – Malignant neoplasms of palate
  • 2B66 – Malignant neoplasms of other or unspecified parts of mouth
  • 2B67 – Malignant neoplasms of parotid gland
  • 2B69 – Malignant neoplasms of tonsil
  • 2B6A – Malignant neoplasms of oropharynx
  • 2B6B – Malignant neoplasms of nasopharynx
  • 2B6C – Malignant neoplasms of piriform sinus
  • 2B6D – Malignant neoplasms of hypopharynx
  • 2B6E – Malignant neoplasms of other or ill-defined sites in the lip, oral cavity or pharynx

Foundation entity

Malignant neoplasms of submandibular or sublingual glands – http://id.who.int/icd/entity/480928417

Allowed postcoordination axes

Part of: 02: Neoplasms