2B81.2

ICD-11 MMS 2026-01

Neuroendocrine neoplasms of appendix

Description

Malignant neoplasms with neuroendocrine differentiation that arise in the appendix. Most are well differentiated neuroendocrine tumours (low and intermediate grade), i.e. carcinoids. Poorly differentiated neuroendocrine carcinomas (high grade) are exceedingly rare.

Coding note from above levels

For use of this category, reference should be made to the mortality coding rules and guidelines in the Reference Guide.

Index terms

  • Neuroendocrine neoplasms of appendix
  • Neuroendocrine tumour of appendix
  • NET- [neuroendocrine tumour] of appendix
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  • appendiceal carcinoid tumour
  • carcinoid tumour of appendix
  • Neuroendocrine tumour, G1 of appendix
  • Neuroendocrine tumour, G2 of appendix
  • Neuroendocrine carcinoma of appendix
  • NEC - [neuroendocrine carcinoma] of appendix
  • Large cell neuroendocrine carcinoma of appendix
  • Small cell neuroendocrine carcinoma of appendix
  • Other specified neuroendocrine neoplasms of appendix
  • Mixed adenoneuroendocrine carcinoma of appendix

Exclusions from above levels

  • http://id.who.int/icd/entity/1965082709 – Malignant mesenchymal neoplasms
  • http://id.who.int/icd/entity/111033337 – Malignant neoplasm metastasis in digestive system
  • http://id.who.int/icd/entity/794095161 – Malignant neoplasms of lip, oral cavity or pharynx
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  • http://id.who.int/icd/entity/879154182 – Neoplasms of central nervous system or related structures
  • http://id.who.int/icd/entity/944754984 – Neoplasms of haematopoietic or lymphoid tissues

Sibling codes

  • 2B81.0 – Adenocarcinoma of appendix
  • 2B81.Y – Other specified malignant neoplasms of appendix
  • 2B81.Z – Malignant neoplasms of appendix, unspecified

Foundation entity

Neuroendocrine neoplasms of appendix – http://id.who.int/icd/entity/1590340268

Allowed postcoordination axes

Part of: 2B81: Malignant neoplasms of appendix › 02: Neoplasms