2C00.3

ICD-11 MMS 2026-01

Squamous cell carcinoma of anus or anal canal

Description

A squamous cell carcinoma (SCC) arising from the anal canal up to the junction with the anal margin (perianal, hair-bearing skin). Human papillomavirus is detected in the majority of cases. Homosexual HIV-positive men have an increased risk of developing anal squamous cell carcinoma in comparison to the general male population. The prognosis is generally better for anal margin SCC than for anal canal SCC. The former are classified with skin tumours.

Coding note from above levels

For use of this category, reference should be made to the mortality coding rules and guidelines in the Reference Guide.

Index terms

  • Squamous cell carcinoma of anus or anal canal

Exclusions from above levels

  • http://id.who.int/icd/entity/1965082709 – Malignant mesenchymal neoplasms
  • http://id.who.int/icd/entity/111033337 – Malignant neoplasm metastasis in digestive system
  • http://id.who.int/icd/entity/794095161 – Malignant neoplasms of lip, oral cavity or pharynx
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  • http://id.who.int/icd/entity/879154182 – Neoplasms of central nervous system or related structures
  • http://id.who.int/icd/entity/944754984 – Neoplasms of haematopoietic or lymphoid tissues

Sibling codes

  • 2C00.0 – Adenocarcinoma of anus or anal canal
  • 2C00.1 – Melanoma of anus or anal canal
  • 2C00.2 – Neuroendocrine neoplasm of anus or anal canal
  • 2C00.Y – Other specified malignant neoplasms of anus or anal canal
  • 2C00.Z – Malignant neoplasms of anus or anal canal, unspecified

Foundation entity

Squamous cell carcinoma of anus or anal canal – http://id.who.int/icd/entity/585238371

Allowed postcoordination axes

Part of: 2C00: Malignant neoplasms of anus or anal canal › 02: Neoplasms