Adenocarcinoma of prostate

Description

An adenocarcinoma arising from the prostate gland. It is one of the most common malignant tumours afflicting men. The majority of adenocarcinomas arise in the peripheral zone and a minority occurs in the central or the transitional zone of the prostate gland. Grading of prostatic adenocarcinoma predicts disease progression and correlates with survival. Several grading systems have been proposed, of which the Gleason system is the most commonly used. Gleason sums of 2 to 4 represent well-differentiated disease, 5 to 7 moderately differentiated disease and 8 to 10 poorly differentiated disease. Prostatic-specific antigen (PSA) serum test is widely used as a screening test for the early detection of prostatic adenocarcinoma.

Coding note from above levels

Includes malignant neoplasm of skin of male genital organs

For use of this category, reference should be made to the mortality coding rules and guidelines in the Reference Guide.

Exclusions from above levels

• http://id.who.int/icd/entity/1965082709 – Malignant mesenchymal neoplasms
• http://id.who.int/icd/entity/879154182 – Neoplasms of central nervous system or related structures
• http://id.who.int/icd/entity/944754984 – Neoplasms of haematopoietic or lymphoid tissues