2D10.4

ICD-11 MMS 2026-01

Medullary carcinoma of thyroid gland

Description

A neuroendocrine carcinoma arising from the C-cells of the thyroid gland. It is closely associated with multiple endocrine neoplasia syndromes. Approximately 10% to 20% of medullary thyroid carcinomas are familial. Patients usually present with a thyroid nodule that is painless and firm. In the majority of cases nodal involvement is present at diagnosis.

Coding note from above levels

For use of this category, reference should be made to the mortality coding rules and guidelines in the Reference Guide.

Index terms

  • Medullary carcinoma of thyroid gland
  • medullary carcinoma with amyloid stroma of thyroid
  • medullary carcinoma with amyloid stroma, unspecified site

Exclusions from above levels

  • http://id.who.int/icd/entity/1965082709 – Malignant mesenchymal neoplasms
  • http://id.who.int/icd/entity/879154182 – Neoplasms of central nervous system or related structures
  • http://id.who.int/icd/entity/944754984 – Neoplasms of haematopoietic or lymphoid tissues

Sibling codes

  • 2D10.0 – Follicular carcinoma of thyroid gland
  • 2D10.1 – Papillary carcinoma of thyroid gland
  • 2D10.2 – Poorly differentiated carcinoma of thyroid gland
  • 2D10.3 – Undifferentiated carcinoma of thyroid gland
  • 2D10.Y – Other specified malignant neoplasms of thyroid gland
  • 2D10.Z – Malignant neoplasms of thyroid gland, unspecified

Foundation entity

Medullary carcinoma of thyroid gland – http://id.who.int/icd/entity/578519098

Allowed postcoordination axes

Part of: 2D10: Malignant neoplasms of thyroid gland › 02: Neoplasms