2E67.13

ICD-11 MMS 2026-01

High grade squamous intraepithelial lesion of vulva, HPV-associated

Description

Squamous intraepithelial lesions (SILs) of the vulva (also known as vulvar intraepithelial neoplasia [VIN]), HPV-associated, are proliferations of squamous cells driven by HPV infection, showing maturation abnormalities and nuclear hyperchromasia that do not extend beyond the basement membrane.

Index terms

  • High grade squamous intraepithelial lesion of vulva, HPV-associated
  • High grade squamous intraepithelial lesion of vulva NOS
  • VIN II Vulvar intraepithelial neoplasia [grade II] NOS
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  • VIN II, HPV associated
  • VIN II-III -[vulvar intraepithelial neoplasia grade 2 -3] moderate and severe dysplasia (deprecated)
  • VIN III Vulvar intraepithelial neoplasia [grade III] NOS
  • VIN III, HPV associated
  • Vulvar intraepithelial neoplasia, classical type
  • Vulvar intraepithelial neoplasia, undifferentiated
  • Vulvar intraepithelial neoplasia, usual (classical)
  • Vulvar intraepithelial neoplasia, usual type

Exclusions from above levels

  • GA13.1 – Low grade squamous intraepithelial lesion of vulva
  • 2E63 – Melanoma in situ neoplasms

Sibling codes

  • 2E67.11 – Vulvar Paget disease
  • 2E67.12 – Vulvar intraepithelial neoplasia, HPV-independent

Foundation entity

High grade squamous intraepithelial lesion of vulva, HPV-associated – http://id.who.int/icd/entity/482153699

Part of: 2E67.1: Carcinoma in situ of vulva › 2E67: Carcinoma in situ of other or unspecified genital organs › 02: Neoplasms