4A84.6

ICD-11 MMS 2026-01

Anaphylaxis secondary to mast cell disorder

Description

Symptoms of anaphylaxis secondary to mast cell disorders result from excessive mast cell mediator release, especially histamine, and may include pruritus and flushing, abdominal pain, diarrhea, dyspnoea, tachycardia, or profound hypotension. It happens in both children and adults, but in adults it can occur even without urticaria pigmentosa lesions. Levels of basal tryptase are constantly high. Fatal anaphylaxis has been described following hymenoptera stings and in the preoperative period.

Index terms

  • Anaphylaxis secondary to mast cell disorder
  • Anaphylaxis secondary to Mastocytosis

Exclusions from above levels

  • 02 – Neoplasms
  • 18 – Complications of pregnancy, childbirth and the puerperium
  • 20 – Developmental anomalies

Sibling codes

  • 4A84.0 – Anaphylaxis due to allergic reaction to food
  • 4A84.1 – Drug-induced anaphylaxis
  • 4A84.2 – Anaphylaxis due to insect venom
  • 4A84.3 – Anaphylaxis provoked by physical factors
  • 4A84.4 – Anaphylaxis due to inhaled allergens
  • 4A84.5 – Anaphylaxis due to contact with allergens
  • 4A84.Y – Other specified anaphylaxis
  • 4A84.Z – Anaphylaxis, unspecified

Foundation entity

Anaphylaxis secondary to mast cell disorder – http://id.who.int/icd/entity/2023405973

Allowed postcoordination axes

Part of: 4A84: Anaphylaxis › 04: Diseases of the immune system