6A21

ICD-11 MMS 2026-01

Schizoaffective disorder

Description

Schizoaffective disorder is an episodic disorder in which the diagnostic requirements of schizophrenia and a manic, mixed, or moderate or severe depressive episode are met within the same episode of illness, either simultaneously or within a few days of each other. Prominent symptoms of schizophrenia (e.g. delusions, hallucinations, disorganisation in the form of thought, experiences of influence, passivity and control) are accompanied by typical symptoms of a moderate or severe depressive episode (e.g. depressed mood, loss of interest, reduced energy), a manic episode (e.g. an extreme mood state characterised by euphoria, irritability, or expansiveness; increased activity or a subjective experience of increased energy) or a mixed episode. Psychomotor disturbances, including catatonia, may be present. Symptoms must have persisted for at least one month. The symptoms are not a manifestation of another medical condition (e.g. a brain tumor) and are not due to the effect of a substance or medication on the central nervous system (e.g. corticosteroids), including withdrawal (e.g. alcohol withdrawal).

Exclusions from above levels

  • QE62 – Uncomplicated bereavement
  • QE84 – Acute stress reaction

Child codes

  • 6A21.0 – Schizoaffective disorder, first episode
  • 6A21.1 – Schizoaffective disorder, multiple episodes
  • 6A21.2 – Schizoaffective disorder, continuous
  • 6A21.Y – Other specified schizoaffective disorder
  • 6A21.Z – Schizoaffective disorder, unspecified

Sibling codes

  • 6A20 – Schizophrenia
  • 6A22 – Schizotypal disorder
  • 6A23 – Acute and transient psychotic disorder
  • 6A24 – Delusional disorder
  • 6A25 – Symptomatic manifestations of primary psychotic disorders
  • 6A2Y – Other specified primary psychotic disorder
  • 6A2Z – Schizophrenia or other primary psychotic disorders, unspecified

Foundation entity

Schizoaffective disorder – http://id.who.int/icd/entity/106339515

Allowed postcoordination axes

Part of: 06: Mental, behavioural or neurodevelopmental disorders