6C4C.2

ICD-11 MMS 2026-01

MDMA or related drug dependence, including MDA

Description

MDMA or related drug dependence, including MDA is a disorder of regulation of MDMA or related drug use arising from repeated or continuous use of MDMA or related drugs. The characteristic feature is a strong internal drive to use MDMA or related drugs, which is manifested by impaired ability to control use, increasing priority given to use over other activities and persistence of use despite harm or negative consequences. These experiences are often accompanied by a subjective sensation of urge or craving to use MDMA or related drugs. Physiological features of dependence may also be present, including tolerance to the effects of MDMA or related drugs, withdrawal symptoms following cessation or reduction in use of MDMA or related drugs, or repeated use of MDMA or pharmacologically similar substances to prevent or alleviate withdrawal symptoms. The features of dependence are usually evident over a period of at least 12 months but the diagnosis may be made if MDMA or related drug use is continuous (daily or almost daily) for at least 3 months.

Excludes

  • 6C4C.0 – Episode of harmful use of MDMA or related drugs, including MDA
  • 6C4C.1 – Harmful pattern of use of MDMA or related drugs, including MDA

Exclusions from above levels

  • QE11.6 – Hazardous use of MDMA or related drugs
  • QE62 – Uncomplicated bereavement
  • QE84 – Acute stress reaction

Child codes

  • 6C4C.20 – MDMA or related drug dependence, including MDA, current use
  • 6C4C.21 – MDMA or related drug dependence, including MDA, early full remission
  • 6C4C.22 – MDMA or related drug dependence, including MDA, sustained partial remission
  • 6C4C.23 – MDMA or related drug dependence, including MDA, sustained full remission
  • 6C4C.2Z – MDMA or related drug dependence, including MDA, unspecified

Sibling codes

  • 6C4C.0 – Episode of harmful use of MDMA or related drugs, including MDA
  • 6C4C.1 – Harmful pattern of use of MDMA or related drugs, including MDA
  • 6C4C.3 – MDMA or related drug intoxication, including MDA
  • 6C4C.4 – MDMA or related drug withdrawal, including MDA
  • 6C4C.5 – MDMA or related drug-induced delirium, including MDA
  • 6C4C.6 – MDMA or related drug-induced psychotic disorder, including MDA
  • 6C4C.7 – Certain specified MDMA or related drug-induced mental or behavioural disorders, including MDA
  • 6C4C.Y – Other specified disorders due to use of methylene-dioxymethamphetamine [MDMA] or related drugs, including methylene-dioxyamphetamine [MDA]
  • 6C4C.Z – Disorders due to use of methylene-dioxymethamphetamine [MDMA] or related drugs, including methylene-dioxyamphetamine [MDA], unspecified

Foundation entity

MDMA or related drug dependence, including MDA – http://id.who.int/icd/entity/473001402

Allowed postcoordination axes

Part of: 6C4C: Disorders due to use of methylene-dioxymethamphetamine [MDMA] or related drugs, including methylene-dioxyamphetamine [MDA] › 06: Mental, behavioural or neurodevelopmental disorders