6C4E.4

ICD-11 MMS 2026-01

Other specified psychoactive substance withdrawal

Description

Other specified psychoactive substance withdrawal is a clinically significant cluster of symptoms, behaviours and/or physiological features, varying in degree of severity and duration, that occurs upon cessation or reduction of use of the specified substance in individuals who have developed dependence or have used the specified substance for a prolonged period or in large amounts. Other specified psychoactive substance withdrawal can also occur when prescribed psychoactive medications have been used in standard therapeutic doses. The specific features of the withdrawal state depend on the pharmacological properties of the specified substance.

Exclusions from above levels

  • 6D72.12 – Amnestic disorder due to other specified psychoactive substance including medications
  • QE62 – Uncomplicated bereavement
  • QE84 – Acute stress reaction

Child codes

  • 6C4E.40 – Other specified psychoactive substance withdrawal, uncomplicated
  • 6C4E.41 – Other specified psychoactive substance withdrawal, with perceptual disturbances
  • 6C4E.42 – Other specified psychoactive substance withdrawal, with seizures
  • 6C4E.43 – Other specified psychoactive substance withdrawal, with perceptual disturbances and seizures
  • 6C4E.4Z – Other specified psychoactive substance withdrawal, unspecified

Sibling codes

  • 6C4E.0 – Episode of harmful use of other specified psychoactive substance
  • 6C4E.1 – Harmful pattern of use of other specified psychoactive substance
  • 6C4E.2 – Other specified psychoactive substance dependence
  • 6C4E.3 – Other specified psychoactive substance intoxication
  • 6C4E.5 – Delirium induced by other specified psychoactive substance including medications
  • 6C4E.6 – Psychotic disorder induced by other specified psychoactive substance
  • 6C4E.7 – Certain other specified psychoactive substance-induced mental or behavioural disorders
  • 6C4E.Y – Other specified disorders due to use of other specified psychoactive substances, including medications
  • 6C4E.Z – Disorders due to use of other specified psychoactive substances, including medications, unspecified

Foundation entity

Other specified psychoactive substance withdrawal – http://id.who.int/icd/entity/2022008391

Allowed postcoordination axes

Part of: 6C4E: Disorders due to use of other specified psychoactive substances, including medications › 06: Mental, behavioural or neurodevelopmental disorders