6E68

ICD-11 MMS 2026-01

Secondary personality change

Description

A syndrome characterised by a persistent personality disturbance that represents a change from the individual’s previous characteristic personality pattern that is judged to be a direct pathophysiological consequence of a health condition not classified under Mental and behavioural disorders, based on evidence from the history, physical examination, or laboratory findings. The symptoms are not accounted for by delirium or by another mental and behavioural disorder, and are not a psychologically mediated response to a severe medical condition (e.g., social withdrawal, avoidance, or dependence in response to a life-threatening diagnosis). This category should be used in addition to the diagnosis for the presumed underlying disorder or disease when the personality symptoms are sufficiently severe to warrant specific clinical attention.

Index terms

  • Secondary personality change
  • organic personality disorder
  • Personality change due to disorders or diseases not classified under mental and behavioural disorders

Excludes

  • 6D10 – Personality disorder
  • 6D70 – Delirium
  • QE50.7 – Personality difficulty

Exclusions from above levels

  • 6C20 – Bodily distress disorder
  • MG30 – Chronic pain
  • MG31 – Acute pain
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  • QE62 – Uncomplicated bereavement
  • QE84 – Acute stress reaction

Sibling codes

  • 6E60 – Secondary neurodevelopmental syndrome
  • 6E61 – Secondary psychotic syndrome
  • 6E62 – Secondary mood syndrome
  • 6E63 – Secondary anxiety syndrome
  • 6E64 – Secondary obsessive-compulsive or related syndrome
  • 6E65 – Secondary dissociative syndrome
  • 6E66 – Secondary impulse control syndrome
  • 6E67 – Secondary neurocognitive syndrome
  • 6E69 – Secondary catatonia syndrome
  • 6E6Y – Other specified secondary mental or behavioural syndrome
  • 6E6Z – Secondary mental or behavioural syndrome, unspecified

Foundation entity

Secondary personality change – http://id.who.int/icd/entity/1324394161

Allowed postcoordination axes

Part of: 06: Mental, behavioural or neurodevelopmental disorders