Sleep-related hypoventilation due to a medication or substance

Description

Sleep-related hypoventilation due to a medication or substance is characterised primarily by chronic hypoventilation and hypercapnia due to prolonged use of medications or substances known to depress ventilatory drive and/or impair respiratory muscle mechanics (e.g. long-acting narcotics, anesthetics, sedative compounds, and muscle relaxants). Hypoxemia is commonly present as well. Hypercapnia may also be present during wakefulness in some patients. Patients can either be asymptomatic or present with complaints of dyspnea, chest tightness, or fatigue. Note: A definitive diagnosis requires objective evidence based on polysomnography with carbon dioxide (CO2) monitoring (by arterial, end-tidal or transcutaneous measures) in the context of medication or substance use that is judged to be causing the symptoms.

Index terms

Sleep-related hypoventilation due to a medication or substance
Sleep-related hypoventilation due to substances including medications

Exclusions from above levels

KB2A – Apnoea of newborn

Sibling codes

7A42.0 – Obesity hypoventilation syndrome
7A42.1 – Congenital central alveolar sleep-related hypoventilation
7A42.2 – Non-congenital central hypoventilation with hypothalamic abnormalities
7A42.3 – Idiopathic central alveolar hypoventilation
7A42.5 – Sleep-related hypoventilation due to medical condition
7A42.6 – Sleep-related hypoxemia due to a medical condition
7A42.Y – Other specified sleep-related hypoventilation or hypoxemia disorders
7A42.Z – Sleep-related hypoventilation or hypoxemia disorders, unspecified

Foundation entity

Part of: 7A42: Sleep-related hypoventilation or hypoxemia disorders › 07: Sleep-wake disorders