Triploidy

Description

A disease caused by one additional set of chromosomes, for a total of 69 chromosomes. Triploidy can present with albuminuria, oedema, or hypertension in the mother. The fetus may present with microcephaly and a placenta that is enlarged and filled with cysts in the case of extra maternally inherited chromosomes, while extra paternally inherited chromosomes cause severe growth problems, an enlarged head, and a small placenta that does not have cysts. Non-mosaic triploidy is highly lethal, and is rarely observed in live births. Confirmation is through observation of an additional set of chromosomes by karyotyping.

Index terms

Triploidy
triploid
triploidy syndrome

Exclusions from above levels

http://id.who.int/icd/entity/733825440 – Inborn errors of metabolism

Sibling codes

LD42.1 – Tetraploidy
LD42.Y – Other specified polyploidies
LD42.Z – Polyploidies, unspecified

Foundation entity

Triploidy – http://id.who.int/icd/entity/1900317965

Part of: LD42: Polyploidies › 20: Developmental anomalies