Catalog

Transient congenital hypothyroidism due to transplacental passage of maternal TSH receptor blocking antibodies

No MMS code

Link to WHO Definition

Transient congenital hypothyroidism due to transplacental passage of maternal TSH receptor blocking antibodies – http://id.who.int/icd/entity/1032159701

Transient congenital hypothyroidism can result from transplacental passage of maternal TSH-binding inhibitory antibodies. This occurs in mothers with autoimmune thyroiditis where immunoglobulin G (IgG) antithyroid antibodies are transmitted across the placenta and block TSH binding sites on the fetal thyroid. This form of congenital hypothyroidism generally resolves within the first 2 to 3 months of life.