Catalog

Carney complex

No MMS code

Link to WHO Definition

Carney complex – http://id.who.int/icd/entity/1051158630

Carney complex is a dominantly inherited hamartoneoplastic syndrome caused bs caused by mutation in the protein kinase A regulatory subunit-1-alpha gene on chromosome 17q. It is characterised by spotty skin and mucosal pigmentation (lentiginosis and blue naevi); overactivity affecting multiple endocrine glands, the manifestations of which may include acromegaly, Cushing syndrome and tumours of the thyroid and testes; and myxomas in the heart, skin and breast.