Catalog

Fetal lower urinary tract obstruction due to posterior urethral valve

No MMS code

Link to WHO Definition

Fetal lower urinary tract obstruction due to posterior urethral valve – http://id.who.int/icd/entity/105479263

Congenital posterior urethral valves cause bladder obstruction in males that can manifest along a spectrum of severity, ranging from disease incompatible with postnatal life to conditions that have such minimal impact that they may not manifest until later in life. Renal insufficiency is caused by PUVs in approximately 10%-15% of children undergoing renal transplant, and approximately one third of patients born with PUVs progress to end-stage renal disease. Moreover, as a result of the obstructive process, increased collagen deposition and muscle hypertrophy can significantly thicken the bladder wall. Hypertrophy and hyperplasia of the detrusor muscle and increases in connective tissue limit bladder compliance during filling.