Catalog

Autoimmune polyendocrinopathy type 2

No MMS code

Link to WHO Definition

Autoimmune polyendocrinopathy type 2 – http://id.who.int/icd/entity/1065249344

This is the most common form of the polyglandular failure syndromes. It is more heterogeneous and has not been linked to one gene. Rather, patients are at a higher risk when they carry a particular human leukocyte antigen genotype (DQ2, DQ8 and DRB1*0404). APS-II affects women to a greater degree than men (75% of cases occur in women).