Catalog
Acute promyelocytic leukaemia with t(15;17)(q24.1;q21.1), PML-RARA
No MMS code
Link to WHO Definition
Acute promyelocytic leukaemia with t(15;17)(q24.1;q21.1), PML-RARA – http://id.who.int/icd/entity/1141137829
An acute myeloid leukaemia (AML) in which abnormal promyelocytes predominate. It is characterised by the t(15;17)(q22;q12) translocation. There are two variants: the typical and microgranular variant. (WHO, 2001). Patients frequently present with disseminated intravascular coagulation.