Catalog

Ankylosing vertebral hyperostosis with tylosis

No MMS code

Link to WHO Definition

Ankylosing vertebral hyperostosis with tylosis – http://id.who.int/icd/entity/120916486

This syndrome is characterised by the association of ankylosing vertebral hyperostosis with hyperkeratosis of the soles and palms. It has been described in at least eight patients, in four sibships spanning two generations of a Greek-Cypriot family. Six other members of the family presented with palmoplantar hyperkeratosis alone. This syndrome is likely to be transmitted as an autosomal dominant trait. It is distinct from diffuse idiopathic skeletal hyperostosis (DISH) which is not a rare disease.