Catalog

Sickle cell disease with crisis with splenic sequestration

No MMS code

Link to WHO Definition

Sickle cell disease with crisis with splenic sequestration – http://id.who.int/icd/entity/1216519906

A disease caused by a HbS mutation in the haemoglobin gene. This disease is characterised by abnormal rigid sickle-shaped red blood cells, crisis, and splenic sequestration. This disease may present with enlargement of spleen, fatigue, shortness of breath, acute chest pain, coughing, dizziness, headaches, pallor of skin or mucous membranes, hypoxia, fever and jaundice. This disease is confirmed by identification of HbS mutation by genetic testing.