Catalog
Osteogenesis imperfecta
Link to WHO Definition
Osteogenesis imperfecta – http://id.who.int/icd/entity/1219932551
Osteogenesis imperfecta (OI) comprises a heterogeneous group of genetic disorders characterised by increased bone fragility, low bone mass, and susceptibility to bone fractures with variable severity. The most clinically relevant characteristic of all types of OI is bone fragility, which manifests as multiple spontaneous fractures.