Catalog

Isolated mitochondrial respiratory chain complex IV deficiency

No MMS code

Link to WHO Definition

Isolated mitochondrial respiratory chain complex IV deficiency – http://id.who.int/icd/entity/1247726031

This refers to isolated coupled electron transfer between an electron donor (such as NADH) and an electron acceptor (such as O2) with the transfer of H+ ions (protons) across a membrane. This diagnosis is with deficiency in Complex IV, with four electrons being removed from four molecules of cytochrome c and transferred to molecular oxygen (O2), producing two molecules of water.