Catalog

Chronic immune demyelinating polyradiculoneuropathy

No MMS code

Link to WHO Definition

Chronic immune demyelinating polyradiculoneuropathy – http://id.who.int/icd/entity/1259747456

Chronic immune demyelinating polyradiculoneuropathy (CIDP) is an acquired peripheral neuropathy of presumed autoimmune etiology, which presents either as a chronically progressive or relapsing-remitting disorder. Symptoms develop subacutely or insidiously over weeks to months. It presents characteristically as a symmetrical polyradiculoneuropathy, with weakness in proximal and distal limb muscles. Motor symptoms are usually more severe than sensory. Sensation, especially proprioception is often impaired, and patients may experience numbness and paraesthesias. Both motor and sensory fibres are affected by multifocal inflammatory demyelination. Cranial nerves can be involved. Spontaneous remissions may occur. M protein can be present in 15 % of patients other associations can be diabetes mellitus and HIV.