Catalog

Chronic hepatitis C, with cirrhosis

No MMS code

Link to WHO Definition

Chronic hepatitis C, with cirrhosis – http://id.who.int/icd/entity/128272532

A liver disease characterised by liver inflammation and advanced fibrosis caused by more than 6 months of infection with the hepatitis C virus, complicated with cirrhosis of the liver. There are often no symptoms. Otherwise, clinical features include fatigue, hard liver edge, muscle wasting, ascites and splenomegaly/portal hypertension. Chronic hepatitis C increases the risks of type 2 diabetes mellitus and cardiovascular disease, which contribute to increased all-cause mortality. Transmission is by blood and body fluid contamination, rarely by sexual transmission and from mother to baby at the time of birth (vertical transmission). Confirmation of the diagnosis is by detection of HCV RNA in the presence of a positive anti-HCV in serum.