Catalog
Hepatosplenic T-cell lymphoma
Link to WHO Definition
Hepatosplenic T-cell lymphoma – http://id.who.int/icd/entity/1301206942
An extranodal, mature T-cell non-Hodgkin lymphoma that originates from cytotoxic T-cells, usually of gamma/delta T-cell type. It is characterised by the presence of medium-size neoplastic lymphocytes infiltrating the hepatic sinusoids. A similar infiltrating pattern is also present in the spleen and bone marrow that are usually involved at the time of the diagnosis.