Catalog

Obesity due to melanocortin-4 receptor deficiency

No MMS code

Link to WHO Definition

Obesity due to melanocortin-4 receptor deficiency – http://id.who.int/icd/entity/132077929

Melanocortin 4 receptor (MC4R) deficiency is the commonest form of monogenic obesity identified so far, and is characterised by severe obesity, an increase in lean body mass and bone mineral density, increased linear growth in early childhood, hyperphagia beginning in the first year of life and severe hyperinsulinaemia, in the presence of preserved reproductive function.