Catalog

Paroxysmal kinesigenic dyskinesia

No MMS code

Link to WHO Definition

Paroxysmal kinesigenic dyskinesia – http://id.who.int/icd/entity/1404801288

Paroxysmal kinesigenic dyskinesia onset is typically during childhood, between 5 and 15 years of age, with males being more commonly affected then females with ratios ranging from 2:1 to 4:1 The condition may be familial or sporadic. Most commonly, the condition is inherited in an autosomally dominant fashion, however there some reports of autosomal recessive inheritance as well. The attacks are typically precipitated by startle or a sudden movement after a period of rest. Many individuals have a PRRT2 gene mutation.