Catalog

Acquired antithrombin deficiency

No MMS code

Link to WHO Definition

Acquired antithrombin deficiency – http://id.who.int/icd/entity/1453338682

Acquired antithrombin deficiency (also known as acquired antithrombin III deficiency) is a deficiency of antithrombin primarily due to consumption or decreased production. It is observed in situations in which activation of the coagulation system is abnormal. Conditions that result in acquired antithrombin deficiency include disseminated intravascular coagulation (DIC), microangiopathic hemolytic anemias due to endothelial damage (such as hemolytic-uremic syndrome), veno-occlusive disease (VOD) (in patients undergoing bone marrow transplantation), sepsis, liver disease, and nephrotic syndrome. Oral contraceptive use and even heparin administration have also been associated with acquired antithrombin deficiency.