Catalog

Idiopathic recurrent stupor

No MMS code

Link to WHO Definition

Idiopathic recurrent stupor – http://id.who.int/icd/entity/1473114049

A recurrent disorder of consciousness of unknown aetiology in which structural brain injury, an epileptic basis, toxic and metabolic disturbances have been excluded. Exogenous benzodiazepine administration has been found to be the cause in a proportion of individuals and this should always be excluded. Clinically there is disturbance of consciousness lasting from hours to days with arousal only with vigorous stimulation and temporary reversal following the administration of flumazenil, a benzodiazepine antagonist, raising the possibility that an endogenous benzodiazepine-like peptide 'endozepine' may be responsible for the disorder.