Catalog

Frontotemporal dementia due to TARDBP mutation

No MMS code

Link to WHO Definition

Frontotemporal dementia due to TARDBP mutation – http://id.who.int/icd/entity/1629386211

FTD due to a mutation in the gene encoding the transactive response DNA binding protein on chromosome 1. Clinically it can present as behavioural variant FTD, motor neuron disease, or FTD with motor neuron disease. Neuropathologically it is associated with TDP-43 positive inclusions.