Catalog
Syndromes with holoprosencephaly as a major feature
Link to WHO Definition
Syndromes with holoprosencephaly as a major feature – http://id.who.int/icd/entity/1723390898
Any syndrome caused by failure of the prosencephalon to divide in two during the antenatal period. These syndromes may present with closely spaced eyes, cyclopia, flat nasal bridge, single maxillary central incisor, small head size, and clefts of the lip and palate.