Catalog

Cortical sporadic Creutzfeldt-Jakob Disease

No MMS code

Link to WHO Definition

Cortical sporadic Creutzfeldt-Jakob Disease – http://id.who.int/icd/entity/1724965250

Cortical sporadic Creutzfeldt-Jakob disease (sCJD) is predominantly characterised by dementia. The accumulated prion protein is MM2 (MM2-cortical) and VV1 which means there is a type 1 abnormal prion protein with valine homozygote at codon 129 polymorphic site of prion protein gene. Ataxic sCJD is characterised by predominant ataxia and accumulation of MV2 or VV2.