Catalog

Sindbis fever

No MMS code

Link to WHO Definition

Sindbis fever – http://id.who.int/icd/entity/1752207841

Sindbis fever is caused by Sindbis virus (SINV) is an enveloped RNA virus of the genus Alphavirus in the virus family Togaviridae. It is arthropod-borne. Sindbis virus is related to Chikungunya alphavirus. Sindbis virus was first isolated from Culex mosquitoes in 1952 in the Nile river delta in Egypt. The first human cases were described in Uganda in 1961, South Africa in 1963, and Australia in 1967. The virus was subsequently acknowledged as the causative agent of a rash-arthritis syndrome. In humans, the symptoms include arthralgia, rash and malaise. The clinical disease caused by SINV infection is known as Pogosta disease (Finland), Ockelbo disease (Sweden), and Karelian fever (Russia). Clinical infection and disease in humans has almost only been reported from Northern Europe (Finland, Sweden, Russian Karelia), where SINV is endemic and where large outbreaks occur intermittently. Cases are occasionally reported in Australia, China, and South Africa.