Catalog

Cytophagic histiocytic panniculitis

No MMS code

Link to WHO Definition

Cytophagic histiocytic panniculitis – http://id.who.int/icd/entity/1978274002

Cytophagic histiocytic panniculitis is a very rare form of panniculitis manifesting as recurrent multiple subcutaneous nodules (which may progressively become ecchymotic and ulcerated), and histologically characterised by lobular panniculitis with lymphocytic and histiocytic infiltration in the subcutaneous adipose tissue. The histiocytic infiltration often involves lymph nodes, bone marrow and other tissues of the reticuloendothelial system. Severe fever, malaise, pancytopenia, hepatosplenomegaly, and mucosal ulcers are common systemic symptoms. The aetiology remains unclear.