Catalog

Autosomal dominant spastic paraplegia type 10

No MMS code

Link to WHO Definition

Autosomal dominant spastic paraplegia type 10 – http://id.who.int/icd/entity/217113223

Autosomal dominant spastic paraplegia syndrome that is categorized as either pure form or complex phenotype. The pure form involves lower limb spasticity, hyperreflexia and extensor plantar responses, presenting in childhood or adolescence. The complex phenotype is associated with additional findings such as peripheral neuropathy with upper limb amyotrophy, moderate intellectual disability and parkinsonism.