Catalog

Paraneoplastic stiff person syndrome variant form

No MMS code

Link to WHO Definition

Paraneoplastic stiff person syndrome variant form – http://id.who.int/icd/entity/233304469

Stiff person syndrome variant form results from a targeted attack on the central nervous system as a consequence of a potentially effective tumour immune response initiated by onco-neural antigens derived from a systemic cancer. Paraneoplastic stiff person syndrome is most commonly associated with the autoantibody amphiphysin-IgG in patients with an underlying breast cancer. Associated neural autoantibodies include: amphiphysin