Catalog

Basement membrane splitting and changes consistent with Alport syndrome

No MMS code

Link to WHO Definition

Basement membrane splitting and changes consistent with Alport syndrome – http://id.who.int/icd/entity/376110430

Electron microscopy shows characteristic irregular thinning, basket weaving and lamellation of the glomerular basement membrane in established disease. Abnormalities in type 4 collagen are found in Alports disease. Hearing loss and other features of Alports syndrome may be present and the combination of clinical and pathology observations may lead to that diagnosis