Catalog

Mitochondrial respiratory chain complex III assembly gene defect

No MMS code

Link to WHO Definition

Mitochondrial respiratory chain complex III assembly gene defect – http://id.who.int/icd/entity/400611280

Complex III is when the Q-cycle contributes to the proton gradient by an asymmetric absorption/release of protons. Two electrons are removed from QH2 at the QO site and sequentially transferred to two molecules of cytochrome c, a water-soluble electron carrier located within the intermembrane space. This diagnosis is with assembly gene defect.