Catalog

Eccrine syringosquamous metaplasia

No MMS code

Link to WHO Definition

Eccrine syringosquamous metaplasia – http://id.who.int/icd/entity/407987403

Eccrine syringosquamous metaplasia describes a distinctive microscopic finding of eccrine duct damage in which an insult, most commonly cytotoxic chemotherapy, has resulted in a transformation from the normal cuboidal to squamous epithelium, which may simulate squamous cell carcinoma. Patients present with erythematous papules, often in a generalised distribution and sometimes with vesicles and pustules. It may also present with acral erythema. Drugs implicated include cytarabine, doxorubicin, cis-platinum and protein kinase inhibitors.