Catalog

Non-alcoholic steatohepatitis with cirrhosis

No MMS code

Link to WHO Definition

Non-alcoholic steatohepatitis with cirrhosis – http://id.who.int/icd/entity/446165311

NASH is histologically defined as the presence of hepatic steatosis and inflammation with hepatocyte injury (ballooning) with or without fibrosis. NASH cirrhosis is an end stage of NASH histologically characterised by fibrosis and regenerative nodules. Depending on context, rates of cirrhosis between 3% and25% have been reported among patients with NASH. In NASH-related cirrhosis, 5-year development of hepatocellular carcinoma and survival rate appear to approximate10% and 70%, respectively. The leading cause of death is liver failure. Steatosis can disappear at the end stage of cirrhosis.