Catalog

Myelopathy due to drugs or medications

No MMS code

Link to WHO Definition

Myelopathy due to drugs or medications – http://id.who.int/icd/entity/538270043

Various drugs and chemical agents have been described as causative agents for myelopathy and myeloneuropathy. Clioquinol was finally found to be the cause of subacute myelo-optic neuropathy, which was seen primarily in Japan from 1955 to 1970 and used to treat intestinal parasitic diseases. The clinical picture can include subacute onset of paraesthesias in the legs, spastic paraparesis, and optic neuropathy. Organophosphate poisoning has been reported as a cause of myelopathy and myeloneuropathy. Various cancer chemotherapeutic agents are known to cause myelopathy and neuropathy. Drugs include cisplatin, cladarabine, doxorubicin, vincristine, cytosine arabinoside, and intrathecal methotrexate.