Catalog

Gamma-delta-beta thalassaemia

No MMS code

Link to WHO Definition

Gamma-delta-beta thalassaemia – http://id.who.int/icd/entity/542750009

A disease caused by a genetically inherited mutation leading to partial or complete deletions of the beta-globin gene complex. This disease is characterised by the inability of this gene to produce gamma, delta and beta chains leading to abnormally structured haemoglobin molecules. This disease may present with fatigue, weakness, shortness of breath, pallor, iron overload, bone deformities and cardiovascular illness. Confirmation is by identification of mutation by genetic testing.