Catalog

Distal hereditary motor neuropathy, Jerash type

No MMS code

Link to WHO Definition

Distal hereditary motor neuropathy, Jerash type – http://id.who.int/icd/entity/578991299

A cluster of patients from consanguineous families was identified in the Jerash region of Jordan. Patients developed weakness and atrophy of the lower limbs associated with pyramidal features in the first decade of life. Weakness subsequently progressed to involve upper limbs. Linkage analysis has mapped the disease to the locus 9p21.1-p12.