Catalog

Sickle cell thalassaemia with crisis

No MMS code

Link to WHO Definition

Sickle cell thalassaemia with crisis – http://id.who.int/icd/entity/579580361

A disease caused by genetically inherited sickle cell (HbS) mutation from one parent and a thalassemia mutation from the other parent. This disease is characterised by abnormal rigid sickle-shaped red blood cells and abnormal production of the beta chain in a haemoglobin molecule and, crisis. This disease may present with pallor, jaundice, iron overload, fatigue, or shortness of breath. Confirmation is by identification of mutations through genetic testing.