Catalog
Primary biliary cholangitis
Link to WHO Definition
Primary biliary cholangitis – http://id.who.int/icd/entity/649193479
Primary biliary cholangitis is characterised by progressive destruction and disappearance of the intralobular bile duct epithelial cells leading to cholestasis (high alkaline phosphatase and GGT {gamma glutamyl transferase}) and eventually liver cirrhosis and liver failure, generally associated with the presence of circulating antimitochondrial antibodies and an increase of serum IgM levels.