Catalog

Isolated mitochondrial respiratory chain complex I deficiency

No MMS code

Link to WHO Definition

Isolated mitochondrial respiratory chain complex I deficiency – http://id.who.int/icd/entity/67580224

This refers to isolated coupled electron transfer between an electron donor (such as NADH) and an electron acceptor (such as O2) with the transfer of H+ ions (protons) across a membrane. This diagnosis is with deficiency in Complex I when two electrons are removed from NADH and transferred to a lipid-soluble carrier, ubiquinone (Q).